Hi, first of all I'm really sorry for not responding in a long while. But secondly, I do think this is a pretty solid way to ctb. Sadly I don't research all of the drugs you mentioned here. But from what I'd found, your antiemetic is pretty solid (though I'd probably choose 60-90 mins prior to make sure both of them works). Now on the concoction, its pretty full of depressants there and from what I can found, Tapentadol works to combine with oxycodone, carisoprodol, and alprazolam to depress your respiratory which could lead to death.
View detailed report of drug-drug and drug-food interactions for alprazolam, amitriptyline, carisoprodol, oxycodone, tapentadol
www.drugs.com
I'd search for tapentadol first but sadly there's no definite lethal dose for that:
Sadly I don't search for the others at the time of the writing. I do know that amitriptyline aren't the leading cause of your ctb since that is an antidepressant and all of the other drugs is a depressant. Same for grapefruit juice.
Now was it reliable? In my opinion, certainly. With combination for drugs like that it's certainly deadly enough to be used as a method of ctb
Was it speedy and peaceful? Yes, since you'll be very likely to just phase out and die after the onset of the drug. If you want to ctb in your own home please make yourself a way to be found to at least make the cleanup far more easier later on (depends on your choice honestly)
The biggest concern for me right now is how do you ingest that concoction? Do you blender all of it into a smoothie or a powder or what exactly? I do want to know about that.
Sure, why not. My DM is open...
I think NDE can be influenced by drugs. Sure, there's also your way of increasing NDE and this paper saying that NDE is still medically inexplainable:
https://pmc.ncbi.nlm.nih.gov/articles/PMC6172100/ (This paper is kinda interesting, please check it out). But I do think that some medication can be used to make your chance of NDE happening. Now was it entirely depends on the drugs? Certainly not, but I do think they play a bigger role than most of the people think of.