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BrainSplatter

BrainSplatter

Member
Oct 31, 2025
43

Could this work?
It says only 8% of the fatalities were from zopiclone alone so most of the suicides were a combination of zopiclone and other drugs I'd definitely keep that in mind
 
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TheCavernousDeep.

Member
Oct 22, 2025
13
The LD50 for Zopiclone is very high when taken alone. The source you cite says most people who died mixed the drug with something else, but the problem is that there's usually very little data on the lethality of drug mixtures. For example, if you do the classical "Benzos + Opioids" OD, yes sure those two drugs potentiating eachother likely lowers the lethal dose substantially (relative to what it would be for taking one drug individually), but I wouldn't have any idea by how much. And then it's just a shot in the dark how much to take.

Talking about your link itself, it's fascinating that the highest (plurality) proportion of OD's came from mixing with AntHistamines. That's a really crazy combo that a bunch of benadryl and Zopiclone would take you out. But people mixed with all sorts of stuff. And the study only includes the fatalities, it doesn't seem to speak to how many people have actually attempted using this OD method (which would be necessary to figure out the fatality rate).

That being said it does give a median blood concentration of people who did succeed in killing themselves with the drug. BUT these aren't monointoxications, so we don't know what the concentrations of other drugs were when they dosed on the Zopiclone.

The hunt for the magic OD continues...
 
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ravenx

ravenx

dead.
Sep 9, 2024
119
The LD50 for Zopiclone is very high when taken alone. The source you cite says most people who died mixed the drug with something else, but the problem is that there's usually very little data on the lethality of drug mixtures. For example, if you do the classical "Benzos + Opioids" OD, yes sure those two drugs potentiating eachother likely lowers the lethal dose substantially (relative to what it would be for taking one drug individually), but I wouldn't have any idea by how much. And then it's just a shot in the dark how much to take.

Talking about your link itself, it's fascinating that the highest (plurality) proportion of OD's came from mixing with AntHistamines. That's a really crazy combo that a bunch of benadryl and Zopiclone would take you out. But people mixed with all sorts of stuff. And the study only includes the fatalities, it doesn't seem to speak to how many people have actually attempted using this OD method (which would be necessary to figure out the fatality rate).

That being said it does give a median blood concentration of people who did succeed in killing themselves with the drug. BUT these aren't monointoxications, so we don't know what the concentrations of other drugs were when they dosed on the Zopiclone.

The hunt for the magic OD continues...
Maybe I'll just do fent
 
T

TheCavernousDeep.

Member
Oct 22, 2025
13
Maybe I'll just do fent
Even that can be unreliable! There's a guy on the forum who did a bunch of ISOTONITAZENE, which is supposed to be even more potent than Fent, and still lived. There's a post about why OD's are so hard here: https://sanctioned-suicide.net/threads/why-ods-fail-miserably-a-guide.181394/

I think the one thing I'll say, is if you're gonna do go for an OD, you've gotta have the math on your side. You've got to really know what the fatal dose is so you can omega overshoot. And the truth is that acquiring drugs is often expensive, illegal, and oftentimes just plane hard. Like sure you can run the numbers on pure fent, but how do you know that your fent is pure?

The closest thing to "the magical OD" that exists is the five drug cocktail in the PPH, and all the drugs in that are a huge pain to source. Not trying to rain on your parade or anything. I too find the idea of ODing very appealing, but it just seems super hard to get right lol (and if you miss judge your dose then maybe u just wake up with hypoxic brain damage and a drug addiction! No fun at all.)
 

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