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Why exactly would a dopamine-blocker prevent you from throwing up? Isn't dopamine a pleasure hormone? What does that have to do with vomiting?

ImSoTired

ImSoTired

So so tired..
Jan 3, 2020
55
Dopamine is used for a wide variety of things in the human body, such as motor control, cognitive function, pleasure/reward, hormone control, ECT.

The subtype of dopamine D2 is located in the chemoreceptor trigger zone, often released from nerve endings in the GI tract. GI irritation releases dopamine and serotonin neurotransmitters, which in turn causes the nausea and vomiting. Dopamine blockers prevent that irritation from happening.
 
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NotWhatIExpected

.
Jan 27, 2020
403
ImSoTired said:
Dopamine is used for a wide variety of things in the human body, such as motor control, cognitive function, pleasure/reward, hormone control, ECT.

The subtype of dopamine D2 is located in the chemoreceptor trigger zone, often released from nerve endings in the GI tract. GI irritation releases dopamine and serotonin neurotransmitters, which in turn causes the nausea and vomiting. Dopamine blockers prevent that irritation from happening.
Click to expand...
Hmm

It's just odd to me that a pleasure chemical would make you throw up
 
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