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A

Anon314

Student
Apr 2, 2025
171
I've read this explained as a "speedball" when it's other more serious drugs - but what do you think of an adhd drug like vyvanse (lisdexamfetamine) with something like tramodol, oxycodone, beta blockers and/or klonopin?

I know all other pill overdoses are said to be full failures and that if you survive there's bad side effects.

I'm sorry if this is a very dumb question.
 
gothbird

gothbird

𝙿𝚘𝚎𝚝 𝙶𝚒𝚛𝚕
Mar 16, 2025
494
It's not a dumb question.

That said, let me be blunt.

Mixing stimulants and opioids like that, even with something as "mild" as vyvanse, is still a form of speedballing. And yes, the effects can be unpredictable and dangerous, but not in a peaceful way. The stimulant speeds your heart up. The opioid slows your respiration down. Your brain gets yanked in opposite directions, and if you don't pass out from one, you might seize from the other. And that's before you add a benzo or a beta blocker to the mix.

Most overdoses from that kind of cocktail don't result in death. They result in organ damage, brain injury, vomiting while unconscious, or waking up hours later in a hospital bed surrounded by people you didn't want to see. Or worse: waking up alone, with half your memory gone and a body that doesn't work the same anymore.

Vyvanse, for what it's worth, is a prodrug. That means it has to metabolise in your liver first before it kicks in. So by the time it's active, you've already potentially slowed your system way down with the other drugs. You could be sedated or disoriented before the stimulant even peaks, which adds a whole layer of confusion and chaos to your body's response.

If you're trying to build something reliable and peaceful? This isn't it. And I'm not saying that to scare you—just to be honest. A lot of people try these kinds of combos thinking it'll just "stop" things. But more often, it just makes the suffering worse.

All the info's out there. Take your time. Read this.
 
  • Informative
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S

snwcolt

BANNED
Apr 1, 2025
99
Yeah speedballing is fun but not reliable way to check out. I recently went on a binge of a massive amount of meth and fentanyl hoping to go out having a good time. It was fun but goddamn felt like I'd been hit by a truck when I came to.
 
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Droso

Droso

Born, survive, reproduce, die.
Dec 23, 2024
257
It's not a dumb question.

That said, let me be blunt.

Mixing stimulants and opioids like that, even with something as "mild" as vyvanse, is still a form of speedballing. And yes, the effects can be unpredictable and dangerous, but not in a peaceful way. The stimulant speeds your heart up. The opioid slows your respiration down. Your brain gets yanked in opposite directions, and if you don't pass out from one, you might seize from the other. And that's before you add a benzo or a beta blocker to the mix.

Most overdoses from that kind of cocktail don't result in death. They result in organ damage, brain injury, vomiting while unconscious, or waking up hours later in a hospital bed surrounded by people you didn't want to see. Or worse: waking up alone, with half your memory gone and a body that doesn't work the same anymore.

Vyvanse, for what it's worth, is a prodrug. That means it has to metabolise in your liver first before it kicks in. So by the time it's active, you've already potentially slowed your system way down with the other drugs. You could be sedated or disoriented before the stimulant even peaks, which adds a whole layer of confusion and chaos to your body's response.

If you're trying to build something reliable and peaceful? This isn't it. And I'm not saying that to scare you—just to be honest. A lot of people try these kinds of combos thinking it'll just "stop" things. But more often, it just makes the suffering worse.

All the info's out there. Take your time. Read this.
Jesus that just sounds like hell. I don't really have good experiences with stimulants. I have a bunch of them stocked up from previous prescriptions, but it's good to know they aren't very useful in any protocol either way.
 
Upvote 0
A

Anon314

Student
Apr 2, 2025
171
Yeah speedballing is fun but not reliable way to check out. I recently went on a binge of a massive amount of meth and fentanyl hoping to go out having a good time. It was fun but goddamn felt like I'd been hit by a truck when I came to.
Oooh yikes. Does not sound ideal. I hope you felt better in not too long a time after the truck feeling
 
Upvote 0
A

Anon314

Student
Apr 2, 2025
171
It's not a dumb question.

That said, let me be blunt.

Mixing stimulants and opioids like that, even with something as "mild" as vyvanse, is still a form of speedballing. And yes, the effects can be unpredictable and dangerous, but not in a peaceful way. The stimulant speeds your heart up. The opioid slows your respiration down. Your brain gets yanked in opposite directions, and if you don't pass out from one, you might seize from the other. And that's before you add a benzo or a beta blocker to the mix.

Most overdoses from that kind of cocktail don't result in death. They result in organ damage, brain injury, vomiting while unconscious, or waking up hours later in a hospital bed surrounded by people you didn't want to see. Or worse: waking up alone, with half your memory gone and a body that doesn't work the same anymore.

Vyvanse, for what it's worth, is a prodrug. That means it has to metabolise in your liver first before it kicks in. So by the time it's active, you've already potentially slowed your system way down with the other drugs. You could be sedated or disoriented before the stimulant even peaks, which adds a whole layer of confusion and chaos to your body's response.

If you're trying to build something reliable and peaceful? This isn't it. And I'm not saying that to scare you—just to be honest. A lot of people try these kinds of combos thinking it'll just "stop" things. But more often, it just makes the suffering worse.

All the info's out there. Take your time. Read this.
They mentioned oxycodone and fentanyl as ones that can work sometimes. I have 200 mg of immediate release oxycodone and I keep wondering if that amount has got potential at all, especially if I use a rectal roa. My sn may not arrive at all, and I may need it longer than the three year shelf life. It depends on many things. So, I've been looking at a lot of other methods pretty thoroughly... and partial hanging or exit bag with gas both seem the most likely. But, those also would be very hard for my skillset/temperament. That's why I'm looking at opiods again.

I am not sure if 200 mg is a safe bet or far from it? I don't use them ever. I know the side effects of overdose include brain damage...which is the big hitch. I've ruled out all other medications as options per the guide, and am glad I never tried that way. (But I hate that this is no exit route. So stuck.) Anyway, you have a really smart math/chemistry mind, if you have any advice I'll gladly take it.
 
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