N & Antiemetics for sensitivities

[ben7]

I've seen so many conflicting posts on this so wanted to make one final post of the topic to help clarify.

If someone has had previous damage from prescription drugs (antidepressants, etc) and is very sensitive to them / nervous of AEs it seems they have two choices:

1. Take no AE with N - from that I've read this is not unheard of but most people seem to advise against.

2. Find a milder AE - outside of Meto it seems the milder ones are Domperidone, and sometimes Dramanine w/ meclazine (but this is also dismissed as too weak by some)

Also - if taking an AE ends up being the decision for those very sensitive, is a) a test essential and b) a 48 hour method or stat dose more advisable?

Any thoughts appreciated - thanks a lot.

 

[markmahomes]

Have you found a solution for this? I have akathisia and am terrified of the meds. I don't want my last 10 mins of consciousness to be a horrible akathisia attack.

 

[Dystopia]

Have you found a solution for this? I have akathisia and am terrified of the meds. I don't want my last 10 mins of consciousness to be a horrible akathisia attack.

Its been said that akithisia symptoms do not normally present themselves until around a day after ingestion so you'd be dead before this even occurs (if it even does)

 

[markmahomes]

Not with me it doesn't....

 

[xLosthopex]

Anyone know which is better, domperidone or stemetil as an AE? I have both and I don't know which would be best to use, my attempt at trying to acquire meto from my GP ended up with him prescribing stemetil instead…

 

[Dystopia]

Anyone know which is better, domperidone or stemetil as an AE? I have both and I don't know which would be best to use, my attempt at trying to acquire meto from my GP ended up with him prescribing stemetil instead…

Stemetil is prochloperazine which has a higher affinity for blocking d2 receptors than metoclopramide but a higher chance of causing side effects. I would personally pick this over domperidone but its up to you.

 

[contramundum]

Hi, it's the first time I'm posting here, I am considering the amitriptyline cocktail and I also have the same doubts about AE that have been posted in the beginning of this thread. Which is better, the regime over two days or the stat dose? I have meto, but not enough for a previous trial. And what about the dose? I've read 2 pills every 8 hours for 2 days or 6 45 minutes before taking the drug, but the leaflet of the pill advises to take one every 12 hours. I am afraid of overdoing it and have extrapyramidal effects. Kind of lost here. Can anyone help me?

 

[Cuppatea856]

I've seen so many conflicting posts on this so wanted to make one final post of the topic to help clarify.

If someone has had previous damage from prescription drugs (antidepressants, etc) and is very sensitive to them / nervous of AEs it seems they have two choices:

1. Take no AE with N - from that I've read this is not unheard of but most people seem to advise against.

2. Find a milder AE - outside of Meto it seems the milder ones are Domperidone, and sometimes Dramanine w/ meclazine (but this is also dismissed as too weak by some)

Also - if taking an AE ends up being the decision for those very sensitive, is a) a test essential and b) a 48 hour method or stat dose more advisable?

Any thoughts appreciated - thanks a lot.

Will Zofran work? I was able to get my Doc to prescribe by telling her I have nausea

 

[peacefulhorizons]

Will Zofran work? I was able to get my Doc to prescribe by telling her I have nausea

Yes. Zofran is a great antiemetic.

 

[contramundum]

Hi, it's the first time I'm posting here, I am considering the amitriptyline cocktail and I also have the same doubts about AE that have been posted in the beginning of this thread. Which is better, the regime over two days or the stat dose? I have meto, but not enough for a previous trial. And what about the dose? I've read 2 pills every 8 hours for 2 days or 6 45 minutes before taking the drug, but the leaflet of the pill advises to take one every 12 hours. I am afraid of overdoing it and have extrapyramidal effects. Kind of lost here. Can anyone help me?

Can anyone advise me on this? Please?