How much quetiapine for sn method ?

[Tralabala]

I take 175mg of quetiapine daily before going to sleep. I was just wondering how much I would be needed? I read that it depends on the weight and height. But still couldnt find how much I should take to make it work. In stan guide units written in nm . I cant understand that. Googled it . It has many meanings. I am 24yo female , 175xm height and 66kg weight. Many thanks for help

 

[Quarky00]

Take what you are given . Do not change dosage . Do not add more antiemetics .It's enough as it is . It replace antiemetics .

"The 13 Others"

What are they?

If you do not take them regularly – DO NOT USE – this section is not for you. They affect over weeks – so only if it is your regular medication. Droperidol, Benperidol, Trifuperidol, Spiperone, Haloperidol, Bromperidol, Lurasidone, Sestindole, Paliperidone, Risperidone, Olanzapine, Clozapine, Quetiapine Order is from the strongest to the weakest . Stan listed with nM (receptor affinity); lower numbers indicate stronger effects.

See more info in FAQ - Antipsychotics

https://sanctioned-suicide.net/threads/sn-resource-page.32633/

 

[Tralabala]

So I would take SN , 175mg of Quetiapine and antacid as gaviscon or rennie . But how much of antacid ,and will I surely will not start vomiting?

 

[Quarky00]

So I would take SN , 175mg of Quetiapine and antacid as gaviscon or rennie . But how much of antacid ,and will I surely will not start vomiting?

Read the provided link :) Stan Guide says how much antacid . And that antacids are not important . FAQ also discuss vomiting .

You take Q at your normal hour as prescribed . No need to change . It has prokinetic properties (empty stomach) that lasts .

I suggest you research that method , read it thoroughly

 

[Yaalya]

Take what you are given . Do not change dosage . Do not add more antiemetics .It's enough as it is . It replace antiemetics .


See more info in FAQ - Antipsychotics

https://sanctioned-suicide.net/threads/sn-resource-page.32633/

but the suicide wiki says double or trible daily dose

"As a rule of thumb, for the stat dose each in each of the antiemetics, double up or triple up the therapeutic daily dose of the antiemetic. For example, for the stat dose, in case the leaflet of the antiemetic advises 6 mg twice a day, take 12 mg or 18 mg (if you're confidence you'll have no side effect). "

sorry my english is bad did i misunderstand something?? My daily dose as part of my treatment is 15mg olanzapine and I want to take 30mg for the SN method right?

 

[Quarky00]

did i misunderstand something??

Yes you did

The question was about Quetiapine which is Anti-Psychotic .

It was not about your Olanzapine which is Anti-emetic ... Follow the instructions -- ignore this thread .

No worries :) Sorry if I caused confusion

 

[autumnal]

Not sure whether you are talking about Quetapine, but if so have a look at my thread on this question. I would say you need a dose of 300-400mg to provide antiemetic effects, and any smaller dose than that is not guaranteed to be sufficient. However it remains unclear whether a single dose at that level provides these effects, or whether you need to be on that dose for a longer period.

 

[Quarky00]

Not sure whether you are talking about Quetapine, but if so have a look at my thread on this question. I would say you need a dose of 300-400mg to provide antiemetic effects.

As said before this is unsubstantiated .

This has been discussed . Prokinetic effects . Quetiapine effective dosage depends on age, weight, condition etc . It's wrong to say you need "high dosages" . No evidence of that .

She took Quetiapine regularly and a dose lower than 400mg at the end. She did not vomit.
It makes sense the higher the dose the more dopamine is blocked. I've been on a dose lower than 400mg for 10 years and I believe it works as an AE for me. The member @Girobatol mentioned was also on a regular long-term dose lower than 400mg and did not vomit.
If you're not taking it regularly, 400mg is likely to knock you out before you can get anywhere near the SN.

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However it remains unclear whether a single dose at that level provides these effects, or whether you need to be on that dose for a longer period.

It is clear that a single big dose is bad .

Whether it's more effective or not , do not suggest such practice .

 

[autumnal]

As said before this is unsubstantiated .

This has been discussed . Prokinetic effects . Quetiapine effective dosage depends on age, weight, condition etc . It's wrong to say you need "high dosages" . No evidence of that .



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It is clear that a single big dose is bad .

Whether it's more effective or not , do not suggest such practice .

I'm going to respectfully disagree and say that the reference I link to in my post is from what I can tell the most definitive source of information on the topic that has appeared anywhere on this forum. I consider that source to be substantiated, more so than the personal opinions or anecdotal evidence of any single forum member (including myself) and their own unique experiences with or personal opinions of dosages.

Like most medications Quetiapine's effective dosage for the intended (psychiatric) purposes can vary as a factor of age, weight and the particular psychiatric condition targeted. However, what is a largely an unintentional purpose (the antiemetic effects) could still conceivably have a reliable dose threshold at which those effects appear, and this can be largely irregardless of individual differences.

A single dose of 300-400mg Quetiapine (which is not a 'big' dose by any means) is only 'bad' to the extent that [a] an isolated one-off dose not taken as part of regular routine dosage may not provide the antiemetic effects that comes from a more regularly-taken dosage of 300-400mg, a sudden starting dosage rather than gradual titration may cause more severe or uncomfortable variations of the normal side-effects of the medication or [c] it may sedate you too quickly that you do not complete the rest of the SN protocol.

Although I stand by my opinion that Quetapine dosages for antiemetic effects is a bit of a nebulous unknown on this board, I think one thing that is fairly obvious is that this complexity means that it is probably not something you would want to start using, either routinely or as a once-off, purely for the purposes of the SN protocol. Especially if other suitable antiemetic drugs are available to you (depending on country of residence) those are far more straightforward. The only people for whom this current topic is relevant are those who are already on Quetapine for psychiatric purposes, but are unsure whether their current dosage is sufficient for antiemetic effects. For those individuals, I would suggest that the resource I linked to is still the most reliable, albeit rare, figure to go on.