Help SN, meto and slow digestion.

[TastySorrow]

I've used metoclopramide non-regularly before to deal with the ocassional nausea that comes with my migraines, but I didn't know it also helps speed up emptying your stomach until I started doing serious research on SN. I do suffer from extremely slow digestion; even when eating regularly I could be up to almost 1 week with no bowel movement other than passing gases. Call it stress, genetics or some unknown underlying condition I don't really know because I've always shrugged it off. It doesn't really matter now though since I feel like my time to CTB is pretty near.

I'm a bit worried that this will affect the absorption of SN since my digestive tract never feels completely empty even when skipping meals or fasting for a whole day or two, especially in my intestines. Will the 5 x 10mg doses of meto previous to SN ingestion from the 48h protocol help with that? Should I maybe experiment before my SN arrives or maybe add an extra day of meto to my protocol?

 

[TastySorrow]

Spent some time reading about meto on the forums and discovered that some people had serious side effects from it after the third 10mg dose in the first day of the 48h regime :/

Should I take the risk or go straight for the stat dose (3 x 10mg 1 hour before SN)?

 

[TastySorrow]

Took the risk and did a whole day of meto as a test, 10mg every 8 hours. It feels like it really helped with my slow metabolism, which is great.

I'm not encouraging anyone to do it, especially since every organism is different.

 

[ihatemyselfwanttodi]

I'm actually in the same boat and have been worried about this. Probably 1 or maybe 2 bowel movements a week.
Decided to try a 10mg meto to see how I react. May keep going for the 48hr method.

 

[sickofwaiting]

i'm also in the same boat. have had acid reflux since childhood, was anorexic for a while, bacterial stomach infection at some point. anything i eat stays in my stomach for days.

 

[ihatemyselfwanttodi]

can anyone else speak to this? I'm really freaking out about this now as I was planning to CTB this weekend, and I'm worrying I'll fail due to slow digestion issues. Definitely thinking I'll lean toward the 48hr meto method or longer now since I know this can cause issues. Was originally just gonna do the stat dose

I've used metoclopramide non-regularly before to deal with the ocassional nausea that comes with my migraines, but I didn't know it also helps speed up emptying your stomach until I started doing serious research on SN. I do suffer from extremely slow digestion; even when eating regularly I could be up to almost 1 week with no bowel movement other than passing gases. Call it stress, genetics or some unknown underlying condition I don't really know because I've always shrugged it off. It doesn't really matter now though since I feel like my time to CTB is pretty near.

I'm a bit worried that this will affect the absorption of SN since my digestive tract never feels completely empty even when skipping meals or fasting for a whole day or two, especially in my intestines. Will the 5 x 10mg doses of meto previous to SN ingestion from the 48h protocol help with that? Should I maybe experiment before my SN arrives or maybe add an extra day of meto to my protocol?

Hey OP I wanted to try to DM you to ask about your meto experience but it won't let me

 

[SchrodingerIsDed]

I've been theorizing about ginger supplement pills. They also speed up gastric emptying. Dunno if you could preload them the week leading up to it if it would have any persistent effects. Alternatively, one could just intentionally consume only foods that absorb quickly and avoid high fiber and such for a couple days prior to the fast, and that would assist.

 

[ihatemyselfwanttodi]

I've been theorizing about ginger supplement pills. They also speed up gastric emptying. Dunno if you could preload them the week leading up to it if it would have any persistent effects. Alternatively, one could just intentionally consume only foods that absorb quickly and avoid high fiber and such for a couple days prior to the fast, and that would assist.

That's an interesting idea. I thought fiber speeds up your system? Isn't that why people take fiber? I'm dumb

 

[ihatemyselfwanttodi]

really worried about failure now.

 

[wayout90]

I'm no doctor or scientist but I really don't think it would make much difference. Gastric emptying refers to the speed with which something moves out of the stomach and into the duodenum which is the first part of the small intestine. The benefit of speeding up the process of gastric emptying, is to reduce the amount of time the SN spends in the stomach. According to the PPH, acids in the stomach will convert some (not all) of the nitrite into nitrate. Whereas it's more quickly and effectively absorbed into the bloodstream once it reaches the small intestine. Hence, why meto is preferred over other antiemetics that don't speed the process of gastric emptying.

If you have a slow digestive system, it's usually because the intestines are having a hard time breaking down food and moving it through the digestive tract. From my understanding, once the SN moves from the stomach to the small intestines, it's able to be more effectively absorbed into the bloodstream and is no longer at risk of being converted into nitrate by stomach acid. I don't imagine it matters how long it might be stuck in the small intestine for those who do have a slow digestive system.

Edited to add: it's also a chemical substance in the same way drugs are chemical substances, so it's processed by the body much differently than the process of digesting food. Having digestive issues doesn't effect the way your body would, for example, process prescription drugs, so I can't see how this would be any different. Just my thoughts

 

[ihatemyselfwanttodi]

I'm no doctor or scientist but I really don't think it would make much difference. Gastric emptying refers to the speed with which something moves out of the stomach and into the duodenum which is the first part of the small intestine. The benefit of speeding up the process of gastric emptying, is to reduce the amount of time the SN spends in the stomach. According to the PPH, acids in the stomach will convert some (not all) of the nitrite into nitrate. Whereas it's more quickly and effectively absorbed into the bloodstream once it reaches the small intestine. Hence, why meto is preferred over other antiemetics that don't speed the process of gastric emptying.

If you have a slow digestive system, it's usually because the intestines are having a hard time breaking down food and moving it through the digestive tract. From my understanding, once the SN moves from the stomach to the small intestines, it's able to be more effectively absorbed into the bloodstream and is no longer at risk of being converted into nitrate by stomach acid. I don't imagine it matters how long it might be stuck in the small intestine for those who do have a slow digestive system.

Edited to add: it's also a chemical substance in the same way drugs are chemical substances, so it's processed by the body much differently than the process of digesting food. Having digestive issues doesn't effect the way your body would, for example, process prescription drugs, so I can't see how this would be any different. Just my thoughts

Hey thank you, this actually gives me some reassurance.

 

[SchrodingerIsDed]

I'm no doctor or scientist but I really don't think it would make much difference. Gastric emptying refers to the speed with which something moves out of the stomach and into the duodenum which is the first part of the small intestine. The benefit of speeding up the process of gastric emptying, is to reduce the amount of time the SN spends in the stomach. According to the PPH, acids in the stomach will convert some (not all) of the nitrite into nitrate. Whereas it's more quickly and effectively absorbed into the bloodstream once it reaches the small intestine. Hence, why meto is preferred over other antiemetics that don't speed the process of gastric emptying.

If you have a slow digestive system, it's usually because the intestines are having a hard time breaking down food and moving it through the digestive tract. From my understanding, once the SN moves from the stomach to the small intestines, it's able to be more effectively absorbed into the bloodstream and is no longer at risk of being converted into nitrate by stomach acid. I don't imagine it matters how long it might be stuck in the small intestine for those who do have a slow digestive system.

Edited to add: it's also a chemical substance in the same way drugs are chemical substances, so it's processed by the body much differently than the process of digesting food. Having digestive issues doesn't effect the way your body would, for example, process prescription drugs, so I can't see how this would be any different. Just my thoughts

Good points. It depends on where their digestion is slow. If they have slow gastric emptying, that's a big problem. If they just don't break down food at the same pace, meh. This is why I suggest to just know how long it takes ibuprofen and other medicines or drugs to hit you when the individual takes them by mouth. It should be 20-60 minutes, depending on the kind of tablet. 20-40 minutes for the gel capsules, 40-60 minutes for tablets. If those are absorbed in normal ranges of time and the effects are felt, there's no problem at all.

That's an interesting idea. I thought fiber speeds up your system? Isn't that why people take fiber? I'm dumb

I'm not really sure either. I don't know much about diet or nutrition. Google says there are two kinds of fiber. One speeds it up, one slows it down.

Oh here you go. I found it. Fiber slows gastric emptying and can also slow medication absorption. If you have difficulties not digesting food, if fiber remains in your intestines, then it could slow down the absorption of the sn. There's a lot of variables and it's hard to say for certain what to do based on "slow digestion". We'd need to know where your digestion is slow and for what reason.

Easiest is to just go workout and lift some heavy things, get sore, then take some ibuprofen and see how long it takes to get rid of the soreness.