Questions regarding drinkable morphine: overdose details/interactive medicines/antiemetic/dosage amount?

[LoveTakesManyForms]

Has anyone here overdosed on drinkable morphine? If so how much did you take, what was it like, did you take an antiemetic, and how did you survive?
Also is there any medication/other that can be taken with it to increase deadliness?
Is an antiemetic needed?
Any particular dose likely to end in CTB?

Thanks in advance.

 

[win32]

i'm pretty sure it would be almost exactly the same as a fentanyl overdose, just harder to do since you need 50-100x more of it due to potency

 

[myopybyproxy]

Do your research first. Your questions show you haven't even read the wikipedia page.

Beyond that, some things to look into that you may find useful include oral morphine's mechanism of action, finding an antiemetic that works on the same pathway (serotonergic, dopaminergic, histamine, muscarinic, alpha adrenergic), the LD50 for humans (other species cannot be extrapolated eg rats tend to be hardier and thus a far higher LD50) and cases of morphine overdose in the literature.

As for 'interactive medicines', the word you are looking for is inhibitors and inducers of the enzyme/s that metabolise morphine.

If you have specific questions after that, I'm happy to explain to the limits of my understanding. But I'm not going to spoon feed you the basics of your method.