Lethal dosage of Propranolol?

[OblivionSeeker]

There are online sources that claim 1 gram Propranolol is lethal. but I read here on SS (somewhere) that it takes 8 grams. Anyone know the accepted ctb dose?

 

[Silver]

The presentation of propranolol toxicity is widely varied, with death reported following ingestion of 2g and survival following ingestion of 8g. It is generally accepted that a dose greater than 1g is potentially life-threatening.

 

[Spitfire]

It is a difficult question to answer.

Every persons body will react a little differently to this drug depending on its current state, and among other factors.

I would not say this is a reliable method for everybody.

The lethal dose needs to be multiplied by several factors.. and the dosage required becomes too great due to the amount, or volume of the drug being consumed. This can make it unreliable for a lot of different reasons.

The aftermath of a failed attempt with this drug may cause permanent damage to the body, and it could drastically reduce the quality of life once recovered.

 

[TooConscious]

You will not die from. Beta blockers unless you're very lucky and bizarre circumstances.

 

[GoodPersonEffed]

You will not die from. Beta blockers unless you're very lucky and bizarre circumstances.

Huh?

 

[Spitfire]

Huh?

I second the inquiry.

There are plenty of fatalities which have happened by way of beta blocker toxicity, let alone from propranolol the most toxic of the beta blockers when it is being used intentionally in this way.

 

[TooConscious]

Huh?

Propranolol will not kill you unless you have underlying health conditions that cause complications. You'll just feel ill.

 

[Spitfire]

That is not true.
10 second search...

Abstract
Propranolol hydrochloride is a beta-adrenergic blocking drug used in a variety of clinical conditions. Overdoses can result in severe hypotensive states usually associated with bradycardia or asystole or with profound myocardial depression. We report on an 18-year-old man who ingested a massive dose of propranolol HCl in a suicide attempt. The patient was brought to the hospital in an unresponsive state within 30 minutes of ingestion. He was initially stabilized but subsequently died nine hours after the drug was ingested.

 

[GoodPersonEffed]

Propranolol will not kill you unless you have underlying health conditions that cause complications. You'll just feel ill.

I'm curious, where did you get this information from?

 

[Silver]

Propranolol will not kill you unless you have underlying health conditions that cause complications. You'll just feel ill.

That's where the 'lethal' bit comes in. Too many propranolol will kill you, even if you have no underlying health conditions.

in the UK there were 52 deaths in 5 years (2012-2017) from propranolol overdose.

Just by googling I can see many news articles about suicide (or accidental death) from propranolol ingestion.

"a case of self-poisoning death due to ingestion of propranolol by a young male physician"

"A schoolgirl has become the second teen to die from mental health pills as her death has been linked to controversial anti-anxiety "beta blocker" drugs...The tragic case emerged two years after the death of [a teenager] 16, who died weeks after being prescribed the drug."

"Student suffered heart failure after taking 50 tablets of anti-anxiety drug Propranolol he had ordered from America."

"A young woman died after she took an overdose of prescribed medication...The cause of death was stated as propranolol toxicity, with depression a contributing factor."

"photographer died from an overdose ... the cause of death to have been a propranolol overdose"

 

[TooConscious]

First I've seen that it's been used often... I thought if somethings so fatal it would be more common. So in theory my next prescription I can attempt to leave. Don't fancy it personally I just think your heart would be battling/resisting interesting to know if it's a horrendous way to go. Maybe combind with benzos/heroin/opiods might help.

 

[Spitfire]

It is not horrendous at all.

It actually kind of felt good. The body begins to feel weird like everything is turning into jelly is the best I can describe it. It is lights out after that.

No feeling of suffocation and no pain, and definitely no panicky feeling because of the nature of what this drug does to block adrenaline. No need to use an antianxiety med.. unless you wanted to for some reason.

It is peacefulness at its finest when it comes to suicide by way of an overdose using pills, in my opinion.

I think the immediate release version will turn the lights off to cause unconsciousness in practically no time flat for most people, like within 15 or maybe 20-30 minutes max after consuming all of the drug.

8-10 hours needs to be allotted as the timeframe to death, or else you could be rescued prior to your dying. If after being rescued and if you are very lucky (lucky as in chance) you could be successfully revived over the course of many hours, then days in the ICU, and possibly weeks being spent in a hospital. And then likely some time in an inpatient psych ward for a few weeks to a month or more after all that is over, for a near full recovery of your health. . . . if you are very lucky.

If things do not work favorably for your recovery, you may have just become a vegetable. Or, severely cognitively challenged, maybe a stroke, maybe a heart attack and/or heart failure, maybe you now will need dialysis for life.. the maybe list is a long one for the possible sequela which could result from a failed attempt when using propranolol.

 

[OblivionSeeker]

Thanks to everyone for the remarks. Some of these antecdotes mention someone taking 50 pills or something like that. what about a much much larger mega dose? for instance 20+mg.

 

[Chesswiz2002]

20+ mg? I believe you mean 20+ gram. I have been interested in this method for sometime. Especially in the concoction of a cocktail of drugs which could potentially guarantee death. There's the classic DDMP2 (Digoxin, Diazepam, Morphine and Propranolol).

But I believe Digoxin is not easy to obtain, and neither is morphine. Diazepam could be replaced by a more common benzo like Clonazepam or Alprazolam. Would Tramadol do in place of Morphine? At least in my country, Tramadol is much easier to obtain. Also, does anybody know how crucial Digoxin is in this cocktail?

 

[asscar.racing]

h

It is not horrendous at all.

It actually kind of felt good. The body begins to feel weird like everything is turning into jelly is the best I can describe it. It is lights out after that.

No feeling of suffocation and no pain, and definitely no panicky feeling because of the nature of what this drug does to block adrenaline. No need to use an antianxiety med.. unless you wanted to for some reason.

It is peacefulness at its finest when it comes to suicide by way of an overdose using pills, in my opinion.

I think the immediate release version will turn the lights off to cause unconsciousness in practically no time flat for most people, like within 15 or maybe 20-30 minutes max after consuming all of the drug.

8-10 hours needs to be allotted as the timeframe to death, or else you could be rescued prior to your dying. If after being rescued and if you are very lucky (lucky as in chance) you could be successfully revived over the course of many hours, then days in the ICU, and possibly weeks being spent in a hospital. And then likely some time in an inpatient psych ward for a few weeks to a month or more after all that is over, for a near full recovery of your health. . . . if you are very lucky.

If things do not work favorably for your recovery, you may have just become a vegetable. Or, severely cognitively challenged, maybe a stroke, maybe a heart attack and/or heart failure, maybe you now will need dialysis for life.. the maybe list is a long one for the possible sequela which could result from a failed attempt when using propranolol.

20+ mg? I believe you mean 20+ gram. I have been interested in this method for sometime. Especially in the concoction of a cocktail of drugs which could potentially guarantee death. There's the classic DDMP2 (Digoxin, Diazepam, Morphine and Propranolol).

But I believe Digoxin is not easy to obtain, and neither is morphine. Diazepam could be replaced by a more common benzo like Clonazepam or Alprazolam. Would Tramadol do in place of Morphine? At least in my country, Tramadol is much easier to obtain. Also, does anybody know how crucial Digoxin is in this cocktail?

it sounds like you made an attempt w propranolol? how much did you take

It is not horrendous at all.

It actually kind of felt good. The body begins to feel weird like everything is turning into jelly is the best I can describe it. It is lights out after that.

No feeling of suffocation and no pain, and definitely no panicky feeling because of the nature of what this drug does to block adrenaline. No need to use an antianxiety med.. unless you wanted to for some reason.

It is peacefulness at its finest when it comes to suicide by way of an overdose using pills, in my opinion.

I think the immediate release version will turn the lights off to cause unconsciousness in practically no time flat for most people, like within 15 or maybe 20-30 minutes max after consuming all of the drug.

8-10 hours needs to be allotted as the timeframe to death, or else you could be rescued prior to your dying. If after being rescued and if you are very lucky (lucky as in chance) you could be successfully revived over the course of many hours, then days in the ICU, and possibly weeks being spent in a hospital. And then likely some time in an inpatient psych ward for a few weeks to a month or more after all that is over, for a near full recovery of your health. . . . if you are very lucky.

If things do not work favorably for your recovery, you may have just become a vegetable. Or, severely cognitively challenged, maybe a stroke, maybe a heart attack and/or heart failure, maybe you now will need dialysis for life.. the maybe list is a long one for the possible sequela which could result from a failed attempt when using propranolol.

it sounds like you made an attempt with propranolol. how much did you take?