For those concerned about vet N additives...

[peacefulhorizons]

Here's a quote from a case study of a N "failure" administered intravenously regarding the inactive ingredients in veterinary pentobarbital...

"Concentrated veterinary solutions (and lower-dose formulations utilized for human use) often contain chemical vehicles, which—while facilitating administration of the medication—can also have significant side effects. These diluents are often alcohol derivatives, for instance, isopropanol, ethanol, and propylene glycol. Side effects of these additives include potentiation of the sedative-hypnotic effects of the barbiturate and metabolic derangements such as lactic acidosis documented from propylene glycol additives [13]."

In addition, for those curious about phenytoin potentiation, here's this:

"Several formulations of pentobarbital-containing veterinary euthanasia agents have varying types of Vaughan-Williams Class-Ib antiarrhythmics, most frequently phenytoin sodium. According to the Euthasol package insert, the rapid administration of these agents reportedly produces cardiotoxic effects during the anesthesia stage of euthanasia by "hastening the cessation of electrical activity of the heart" via interference with myocardial sodium channel function. In this patient, the clinical toxicity observed stemmed directly from sedative-hypnotic toxicity and likely very little from the phenytoin."

Here's the article: https://www.hindawi.com/journals/criem/2016/6270491/

 

[Huntfish34]

That all sounds pretty damn interesting and complex. Thank you for sharing.