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F

FlyingTortoise

Member
Aug 20, 2025
18
The PPH isn't clear.

It says (+/-) propranolol in both parts of the text.
 
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nobodycaresaboutme

nobodycaresaboutme

maybe my English kinda sucks
Jun 30, 2025
521
I think you don't need propranolol. Whether and when to take will have no impact on your protocol. Some members took it 45 minutes before, some did right after the SN drink.

Question: Do I need to take propranolol?
Answer: propranolol is a beta-blocker, as you know. It's not necessary for the protocol. It's just sometimes advised to slow the tachycardia that will occur, once you ingest the salt. That rapid heart-rate causes panic, in most people. You don't have to have it. It won't accelerate the process. You just have to be able to push through it, knowing that it's temporary. (Ppeh doesn't recommend it)
 
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cowboypants

cowboypants

From milkyway
May 7, 2024
559
You can take it before or after sn. I plan to take 80mg with antiemetics and the rest 320mg after or with sn. I feel I would get too weak with that high of a dose.
 
unluckysadness

unluckysadness

Elementalist
Jul 9, 2025
868
The PPH isn't clear.

It says (+/-) propranolol in both parts of the text.
I have the same questions about propranolol. I hope that the next PPH version will give some update about it
 
R

rozeske

Maybe I am the problem
Dec 2, 2023
4,148
Propranalol is optional, hence the +/- as there is still a debate on the benefit or otherwise of using a B-blocker. Antimatic or antimatic + B-blocker 40 minutes before sn.
 
L

ladidaok

Member
Sep 25, 2025
29
EDIT: I think I'm just going to stick to 400.

I'm susceptible to vomiting, and this cocktail (at 400 mg) already is likely to make me vomit



Bumping this thread

Does anyone know if it's okay to take more than 400 mg propanolol?

My main priority is minimizing anxiety and pain/discomfort during the time I'm conscious

So, if extra propanolol could help ease me during the brief period between taking and going unconscious, I'm all for it

For reference, I have access to about 900 mg
 
claracatchingthebus

claracatchingthebus

I request my username and all posts be deleted.
Jun 22, 2025
561
Propranolol makes a person's heart beat slower even when there's more adrenaline. It's a beta blocker and blocks adrenaline.

If your cells aren't getting oxygen for some reason (ie, you've decided to prevent your hemoglobin from transporting oxygen for some reason and so have ingested an extremely fatal poison), I would guess a heart would beat much faster in response since it would "think" that it's not beating fast enough and that's why there's not enough oxygen (because why would hemoglobin not carry oxygen properly unless it wasn't beating fast enough?). Usually when a heart needs to beat faster, adreleline is what is realized to kick that process into high gear.

As someone who once was put on seroquel doses that were way too fucking high and caused all sorts of horrible side-effects because of a terrible doctor who was mean to me when i was involuntarily hospitalized, I can tell you that having your heart beat much much faster is not fun at all and is very distressing. Having your heart beat super fast is really not fun.

This is not meant to encourage any suicides. If you're able to get better, I hope you do.
 
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