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W

wham311

Enlightened
Mar 1, 2025
1,203
I do think enough blood pressure medication would work. A mix of propranolol, prazosin, remeron gabapentin should actually be ok in theory no?

Propranolol marks lethal dosage at 2000mg which is doable. Remeron is a very small pill and reduces the volume of propranolol.

Just spitballing
 
quietwoods

quietwoods

Easypeazylemonsqueezy
May 21, 2025
410
It's not so much that they rarely work, it's more that they are unreliable or require consuming immense amounts of pills, and ODing can cause damage to your body that is irreversible.

Kidney damage is common with ODs from blood pressure meds. You damage them enough and you may need dialysis, which if you think your life sucks now what till you need dialysis multiple times a week.

And that all of the more lethal ODs require prescriptions or acquiring from questionable sources, making acquisition difficult.

Propranolol is stated at 2g, but the doctor from Denmark has it listed as 8g to be reliable.

ODs are just a gamble with major risks involved. I would suggest reading about the DDMA method if you want to learn about an actually lethal mixture.
 
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nobodycaresaboutme

nobodycaresaboutme

maybe my English kinda sucks
Jun 30, 2025
166
Propranolol Hydrochloride oral LD50 is 466 mg/kg in rats.
This means 146 * 160mg tablets of propranolol are needed for a 50kg person to achieve no more than 50% success rate.
In Japan (my country) only 10mg tablets are prescribed and the number of tablets is 2330.
It's also worth noting that failed attempts can cause organ damages as @quietwoods mentioned.
It doesn't look worth trying for me...
 
Last edited:
W

wham311

Enlightened
Mar 1, 2025
1,203
Propranolol Hydrochloride oral LD50 is 466 mg/kg in rats.
This means 146 * 160mg tablets of propranolol are needed for a 50kg person to achieve no more than 50% success rate.
In Japan (my country) only 10mg tablets are prescribed and the number of tablets is 2330.
It's also worth noting that failed attempts can cause organ damages as @quietwoods mentioned.
It doesn't look worth trying for me...
Rats to people and other numbers have been kind of picked apart in the od mega
 
N

Nightfoot

Experienced
Aug 7, 2025
259
Overdoses are unreliable and can leave you in worse shape than before.
 
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