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J

January-ish

Member
Aug 23, 2020
17
I plan to ingest N and I am aware that nothing else is really absolutely "needed"

That said, I like the idea of doing extra even just for my own peace of mind to lower the chance I could experience tachycardia. I have seen for some methods (not asking for advice on method here just ancillary information) that a beta-blocker is sometimes included in protocol. I have a prescription already for an alpha blocker called prazosin.

Does anyone understand the difference between the two (alpha and beta blockers) well enough to explain if an alpha blocker could inhibit a successful attempt? Or perhaps augment the effects? Or maybe its completely neutral in which case I would take it anyways just for the psychological peace? I will be taking it likely at least a couple hours ahead of time since it is a normal every day medication for me and tends to be effective for half a day.
 
Cameron Diazepam

Cameron Diazepam

Member
Dec 25, 2021
21
Both are blood pressure medications that are also used for anxiety, though prazosin is more common for PTSD nightmares and beta blockers are more known for reducing the physical effects of anxiety like stage fright. I think it would be more dependent upon what works for you and your biology in terms of anxiety reduction for any panic with the survival instinct than any additive benefits to the effects of N. In theory you might be able to depress the heart rate further but why risk unpredictable effects when N alone will do the job?
 
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mindcancer

mindcancer

Member
Mar 27, 2021
87
α-blockers primarily work via vasodilation which decreases blood pressure and vascular resistance. It may relieve stress and lower blood tension, but it doesn't compare to β-blockers who directly slower the heart rate. You might still feel the discomfort of tachycardia by taking prazosin. α1-blockers acts on vascular smooth muscles and not the heart, whereas β1-blockers acts directly on the heart muscle thereby reducing vascular output from the primary source.
 
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J

January-ish

Member
Aug 23, 2020
17
Thanks so much for responding. I'm going to ctb the day after tomorrow.

What I hear you guys saying is… that an alpha-blocker might not help any with the N, but it also wouldn't hurt?

I do take it for ptsd and nightmares.
 

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